A man and his wife were arrested at a Florida airport Tuesday after refusing to get off an American Airlines flight when the crew became concerned about the man’s bloodied head.

The pair was escorted off a Las Vegas-bound plane in handcuffs at Miami International Airport by police officers after crew members grew concerned about the potential bio-hazard, according to local reports.

Eugenio Ernesto Hernandez-Garnier, 27, boarded the plane with a bloody head and a bandage that appeared to be falling off, according to a live video streamed by his wife on TikTok.

Crew members initially asked him to clean the bloody area — which appears to be the aftermath of a hair transplant surgery — and replace his bandages but he said he didn’t have any extras to do so, Local10 reported.

They then told him that he must deboard the plane because they were concerned both about his medical condition and the potential for contamination inside the cabin, according to arrest records reviewed by the local news station.

But he and his 32-year-old wife, Yusleydis Blanca Loyola, refused to comply, police said.

Loyola reportedly said if she and her husband couldn’t fly, “no else can either,” according to the report.

The American Airlines crew called police who boarded the plane and also asked the couple to leave.

They again refused so the cops placed them in handcuffs and forcibly removed them as Loyola yelled in Spanish that her husband just had surgery and it was dried blood, according to clips on TikTok.

A crowd of all the other passengers on the flight who were also forced to deplane over health concerns cheered and clapped as a teary Loyola filmed herself and her husband walking through the gate.

The husband and wife were first brought to the hospital to be evaluated for the bleeding before they were transported to Turner Guilford Knight Correctional Center, authorities said.

Loyola also had cosmetic surgery while visiting Miami, according to videos she posted to TikTok under the name “La Pony.”

Commenters wrote that they were not cleared by the doctor to fly before they got on the plane headed back to Vegas just a few days after their surgeries.

Loyola is wearing a hospital gown in her mugshot, while Hernandez-Garnier is pictured with blood drips down his head in his mugshot.

They are facing charges of trespassing after a warning and resisting an officer without violence.

The Post reached out to American Airlines for comment.