CHICAGO — For weeks, teams have wanted no part of facing Aaron Judge.

Opposing managers have been much happier to flash four fingers as he steps into the box, intentionally walking him to face anybody but the Yankees slugger who has been on an otherworldly tear for the past few months.

Then the unthinkable happened Wednesday night, and it gave way to history.

The White Sox actually intentionally walked Juan Soto to bring up Judge, who responded by crushing a three-run shot — the 300th home run of his career — as the Yankees ran away with a 10-2 win at Guaranteed Rate Field.

Judge became the fastest player in MLB history to reach 300 career home runs, doing it in his 955th game and 3,431st at-bat.

The previous record holders were Ralph Kiner (1,087 games) and Babe Ruth (3,831 at-bats).

The milestone blast came in the eighth inning on a 3-0 pitch from righty reliever Chad Kuhl, who threw an inside sinker that Judge (2-for-4, walk) pounced on for a 361-foot bullet and his 43rd home run of the season.

It put the Yankees (72-50) ahead 9-2 and ensured they got out of the South Side with a series win against the historically bad White Sox (29-93).

The Yankees led 6-2 with one out in the eighth and a runner on second base when they opted to intentionally walk Soto with first base open.

It marked the first time Soto — who belted four home runs in a span of five plate appearances between Tuesday and Wednesday — had been intentionally walked this season, the payoff of having Judge bat behind him.

Judge’s road to 300 included breaking Roger Maris’ American League single-season record in 2022 with 62 home runs and setting the MLB rookie record with 52 home runs in 2017 (which has since been broken by Pete Alonso).

The 32-year-old, who is the favorite to take home his second career MVP this season, finished Wednesday night batting .333 with a 1.174 OPS and on pace for 57 home runs.

Before Judge made history, the Yankees trailed 2-1 entering the seventh inning.

It took some smart, aggressive baserunning by Oswaldo Cabrera — starting his second straight game at third base for the injured Jazz Chisholm Jr. — to help the Yankees tie the game 2-2 in the seventh inning.

Cabrera was at second base with one out when Alex Verdugo drilled a fly ball into the right-center field gap.

Right fielder Dominic Fletcher ran it down for the catch, but tripped over center fielder Luis Robert Jr. and stumbled onto the warning track.

Cabrera was tagging the whole way and never broke stride around third base, diving in to score just ahead of the tag.

Then, after a walk from Soto and double by Judge, Austin Wells delivered the clutch hit the Yankees had been missing with a two-out, two-run single the other way for the 4-2 lead.

Cabrera added an RBI single in the eighth inning and scored on an RBI double from Verdugo that made it 6-2 and somehow convinced the White Sox to intentionally walk Soto to bring up Judge.

Right after Judge hit No. 300, Wells made it back-to-back with his ninth home run of the season to cap off a 3-for-5 night.

Will Warren was solid in his third spot start in as many weeks, tossing five innings of two-run ball.